Osseointegration: hierarchical designing encompassing the macrometer, micrometer, and nanometer length scales.

@article{Coelho2015OsseointegrationHD,
  title={Osseointegration: hierarchical designing encompassing the macrometer, micrometer, and nanometer length scales.},
  author={Paulo G. Coelho and Ryo Jimbo and Nick Tovar and Estevam Augusto Bonfante},
  journal={Dental materials : official publication of the Academy of Dental Materials},
  year={2015},
  volume={31 1},
  pages={
          37-52
        }
}

Figures from this paper

Revisiting the Role of Implant Design and Surgical Instrumentation on Osseointegration
TLDR
How the different metallic device design length scales’ interplay (macro, micro, and nano) affects the bone response and how its understanding may affect the next generation of metallic device designing for osseointegration is focused on.
Nano-scale modification of titanium implant surfaces to enhance osseointegration.
The effect of controlled microrobotized blasting on implant surface texturing and early osseointegration
TLDR
Results showed initial osteogenic tissue interaction at one week and new bone in intimate contact with all implant surfaces at 6 weeks, and higher bone-to-implant and bone area fraction occupancy were observed for the high texture pattern microrobotized blasted surface relative to others.
Impact of Dental Implant Surface Modifications on Osseointegration
TLDR
This paper provides a comprehensive overview of surface modifications that beneficially alter the topography, hydrophilicity, and outer coating of dental implants in order to enhance osseointegration in healthy as well as in compromised bone.
Histological and Nanomechanical Properties of a New Nanometric Hydroxiapatite Implant Surface. An In Vivo Study in Diabetic Rats
TLDR
Nano-hydroxyapatite coated implants presented promising biomechanical results and could be an important tool to compensate impaired bone healing reported in diabetics.
Mechanical aspects of dental implants and osseointegration: A narrative review.
Alveolar Ridge Expansion: Comparison of Osseodensification and Conventional Osteotome Techniques
TLDR
The combined osseodensification drilling-alveolar ridge expansion technique showed increased evidence of osseointegration and implant primary stability from a histologic and biomechanical standpoint, respectively.
Multi-Scale Surface Treatments of Titanium Implants for Rapid Osseointegration: A Review
TLDR
The advances in multi-scale surface technology of titanium implants to accelerate the osseointegration process are summarized and functionalized coatings with organic and non-organic loadings suggest good prospects for the future of modern biotechnology.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 195 REFERENCES
The impact of a modified cutting flute implant design on osseointegration.
  • R. Jimbo, N. Tovar, P. Coelho
  • Materials Science, Medicine
    International journal of oral and maxillofacial surgery
  • 2014
Osteoprogenitor response to defined topographies with nanoscale depths.
Characterization of five different implant surfaces and their effect on osseointegration: a study in dogs.
TLDR
The five surfaces evaluated were osteoconductive and resulted in high degrees of osseointegration and biomechanical fixation, and the alumina-blasting surface presented the highest average surface roughness and mean root square of the surface values.
Nano Hydroxyapatite-coated Implants Improve Bone Nanomechanical Properties
TLDR
A nanoscale hydroxyapatite (HA)-coated implant surface is described and hypothesize that it will hasten osseointegration and improve its quality relative to that of non-coated implants, validating the postulated hypothesis.
Immediate occlusal loading of NanoTite PREVAIL implants: a prospective 1-year clinical and radiographic study.
TLDR
Although limited to the short follow-up, immediate loading of NanoTite Prevail implants seems to be a viable option in implant rehabilitation, at least when a good initial fixation is achieved.
The effect of chemical and nanotopographical modifications on the early stages of osseointegration.
TLDR
Chemical modifications used in the present study were capable of producing a particular nanotopography, and together with the ions present at the implant surface, may explain the increased removal torque values after a healing period of 4 weeks.
Discrete calcium phosphate nanocrystalline deposition enhances osteoconduction on titanium-based implant surfaces.
TLDR
Osteoconduction was assessed, as a function of bone-implant contact, on a total of 1087 BSEI micrographs and submitted to rigorous statistical analyses, and showed both the important effects of anatomic location on bone ingrowth and the significant increase in osteoconductions as a result of the enhanced surface nanotopography obtained by the CAP nanocrystals.
...
1
2
3
4
5
...