Osmotic shock induction of capsule synthesis in Escherichia coli K-12.

@article{Sledjeski1996OsmoticSI,
  title={Osmotic shock induction of capsule synthesis in Escherichia coli K-12.},
  author={Darren D Sledjeski and Susan Gottesman},
  journal={Journal of bacteriology},
  year={1996},
  volume={178 4},
  pages={1204-6}
}
The genes (cps) involved in the synthesis of the colanic acid capsular polysaccharide in Escherichia coli K-12 are transcriptionally regulated by numerous proteins. Two of these, RcsB and RcsC, share homology with two-component regulatory elements that respond to environmental stimuli. Osmotic shock by sucrose or NaCl transiently increased transcription of a cpsB::lacZ fusion. RcsC and RcsB were essential for osmotic induction of colanic acid synthesis. In contrast to observations in some other… CONTINUE READING