Osmotic regulation of L-proline transport in Salmonella typhimurium.

  title={Osmotic regulation of L-proline transport in Salmonella typhimurium.},
  author={V J Dunlap and Laszlo N Csonka},
  journal={Journal of bacteriology},
  volume={163 1},
The transport of proline is important for the adaptation of Salmonella typhimurium to osmotic stress because exogenous proline permits the growth of the organism in media of elevated osmotic strength that would otherwise be toxic. Measurements of the rate of [3H]proline transport in S. typhimurium indicated that the organism has two distinct proline permeases, the ProU and the ProP systems, whose activities increase more than fivefold as a consequence of growth in media containing 0.3 M NaCl or… CONTINUE READING