Osmotic forces driving water reabsorption in the proximal tubule of the rat kidney.

@article{Green1989OsmoticFD,
  title={Osmotic forces driving water reabsorption in the proximal tubule of the rat kidney.},
  author={Robert S. Green and Gerhard Giebisch},
  journal={The American journal of physiology},
  year={1989},
  volume={257 4 Pt 2},
  pages={F669-75}
}
Simultaneous microperfusion of proximal tubules and peritubular capillaries in kidneys of rats anesthetized with Inactin was used to measure reabsorption of fluid in response to an imposed osmotic gradient. The tubular fluid was isotonic and the peritubular capillaries were made hypertonic with NaCl or NaHCO3. Mean gradients and ionic fluxes were measured. When no gradient was imposed tubular fluid became hypotonic and rate of fluid reabsorption was 0.700 nl.mm-1.min-1. Imposition of a 25 mM… CONTINUE READING

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