Osmotic effectors in kidneys of xeric and mesic rodents: corticomedullary distributions and changes with water availability

@article{Yancey1988OsmoticEI,
  title={Osmotic effectors in kidneys of xeric and mesic rodents: corticomedullary distributions and changes with water availability},
  author={Paul H. Yancey},
  journal={Journal of Comparative Physiology B},
  year={1988},
  volume={158},
  pages={369-380}
}
Urea, sodium, the methylamines glycine betaine and glycerophosphorylcholine (GPC), and the polyols sorbitol and myo-inositol are reported to be the major osmolytes in kidneys of laboratory mammals. These were measured (millimoles per kilogram wet weight) in kidney regions and urines of three species of wild rodents with different dehydration tolerances: the pocket mousePerognathus parvus (xeric), voleMicrotus montanus (mesic), and deer mousePeromyscus m. gambeli (intermediate). In animals kept… CONTINUE READING
Highly Cited
This paper has 29 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Dehydration increases organic osmolytes in the renal inner medulla (abstract)

SR Gullans, JD Blumenfeld, +3 authors SC Hebert
Kidney Int • 1988
View 4 Excerpts
Highly Influenced

The role of methylamines and free amino acids in protection of mammalian kidney

KD Finley
1984
View 6 Excerpts
Highly Influenced

Free myo-inositol in canine kidneys: selective concentration in the renal medulla.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine • 1982
View 5 Excerpts
Highly Influenced

Monitoring of osmolyte levels in pig papillary collecting tubules (abstract)

Y Boulanger, P Vinay, A Tejedor, J Noel, P Legault
Kidney Int • 1988
View 1 Excerpt

A sorbital gradient in rat renal medulla (abstract)

PJ Oates, KJ Goddu
Kidney Int • 1987
View 2 Excerpts

Slow changes in aldose reduetase and rapid changes in sorbitol flux mediate osmoregulation by renal medullary cells

S Bagnaseo, J Bedford, M Burg
Fed Proc • 1987