Osmotic demyelination disorders: central pontine and extrapontine myelinolysis

@article{Brown2000OsmoticDD,
  title={Osmotic demyelination disorders: central pontine and extrapontine myelinolysis},
  author={W. D. Brown},
  journal={Current Opinion in Neurology},
  year={2000},
  volume={13},
  pages={691-697}
}
  • W. D. Brown
  • Published 2000
  • Medicine
  • Current Opinion in Neurology
Focal symmetric demyelination in the central nervous system may be precipitated by aggressive correction of a hyper- or hypo-osmolar state and until recently has been associated with a high rate of morbidity and mortality. Specific anatomical locations are more susceptible to demyelination than others, although the mechanism of injury is unknown. Classic clinical and anatomical descriptions associated with a central pontine location have been supplemented by descriptions of patients with… Expand
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TLDR
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