Osmotic activation of the Na+/H+ antiporter during volume regulation.

@article{Grinstein1994OsmoticAO,
  title={Osmotic activation of the Na+/H+ antiporter during volume regulation.},
  author={Sergio Grinstein and M Woodside and Greg G Goss and Andr{\'a}s Kapus},
  journal={Biochemical Society transactions},
  year={1994},
  volume={22 2},
  pages={
          512-6
        }
}
Introduction Cellular water content, which accounts for 70% of the cellular mass, is the main determinant of cell volume. In animal cells, which are devoid of rigid walls, it is generally accepted that the water content is dictated by the amount of osmotically active cellular particles. Inorganic ions constitute a major fraction of the cellular osmolytes. It is therefore not surprising that changes in the cellular content of these ions underlie the homeostatic processes whereby many cell types… CONTINUE READING

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