Osmotic Pressure Induced Coupling between Cooperativity and Stability of a Helix-Coil Transition.

  title={Osmotic Pressure Induced Coupling between Cooperativity and Stability of a Helix-Coil Transition.},
  author={Artem Badasyan and Sh. A. Tonoyan and Achille Giacometti and R. Podgornik and V. Adrian Parsegian and Yevgeni Mamasakhlisov and Vladimir F. Morozov},
  journal={Physical review letters},
  volume={109 6},
Most helix-coil transition theories can be characterized by three parameters: energetic, describing the (free) energy cost of forming a helical state in one repeating unit; entropic, accounting for the decrease of entropy due to formation of the helical state; and geometric, indicating how many repeating units are affected by the formation of one helical state. Depending on their effect on the helix-coil transition, solvents or cosolutes can be classified with respect to their action on these… 

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