Osmotic Myelinolysis Following Chronic Hyponatremia Corrected at An Overall Rate Consistent with Current Recommendations

@article{Dellabarca2004OsmoticMF,
  title={Osmotic Myelinolysis Following Chronic Hyponatremia Corrected at An Overall Rate Consistent with Current Recommendations},
  author={C. Dellabarca and K. Servilla and B. Hart and G. Murata and A. Tzamaloukas},
  journal={International Urology and Nephrology},
  year={2004},
  volume={37},
  pages={171-173}
}
  • C. Dellabarca, K. Servilla, +2 authors A. Tzamaloukas
  • Published 2004
  • Medicine
  • International Urology and Nephrology
  • Rapid correction of chronic hyponatremia (CH) may lead to the development of osmotic myelinolysis (OM), a condition with high mortality and high incidence of devastating neurological sequelae. Treatment guidelines suggest “safe” overall rates of correction of serum sodium concentration ([Na]s) over the first 24 and 48 hours of treatment of CH. We report a patient with CH who developed fatal OM despite overall rates of correction of [Na]s that were within the recommended rates. The potential… CONTINUE READING
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