Osmoregulation of plasma vasopressin in myxedema.

  title={Osmoregulation of plasma vasopressin in myxedema.},
  author={Yasuo Iwasaki and Yutaka Oiso and Keishi Yamauchi and Kiyoshi Takatsuki and Kazunao Kondo and Hideo Hasegawa and Akio Tomita},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={70 2},
We studied osmoregulation of plasma vasopressin (AVP) in eight patients with untreated myxedema due to primary hypothyroidism. All patients had severe thyroid hormone deficiency due to chronic thyroiditis and had been receiving no medication at the time of this study. AVP release was defined by 5% hypertonic saline infusion test in all patients, and urinary diluting capacity was estimated by the iv water-loading tests in five patients. Plasma AVP was measured by sensitive and specific RIA. The… CONTINUE READING
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