Osmole gap in neurologic-neurosurgical intensive care unit: Its normal value, calculation, and relationship with mannitol serum concentrations.

@article{GarcaMorales2004OsmoleGI,
  title={Osmole gap in neurologic-neurosurgical intensive care unit: Its normal value, calculation, and relationship with mannitol serum concentrations.},
  author={Edgar J Garc{\'i}a-Morales and Rohit Cariappa and Curtis A. Parvin and Mitchell Scott and Michael N Diringer},
  journal={Critical care medicine},
  year={2004},
  volume={32 4},
  pages={986-91}
}
OBJECTIVE To determine a) if the admission osmole gap, the difference between osmolality and osmolarity, is the same in the neurologic-neurosurgical intensive care unit (NNICU) population as in healthy controls; b) which of 11 osmole gap formulas, or osmolality, correlates best with mannitol serum concentrations; c) whether osmole gap correction for plasma water content improves this correlation; and d) whether the osmole gap can predict mannitol serum concentrations. DESIGN Prospectively… CONTINUE READING

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