Osmolality: a physiological long-term regulator of lumbar sympathetic nerve activity and arterial pressure.

@article{Scrogin1999OsmolalityAP,
  title={Osmolality: a physiological long-term regulator of lumbar sympathetic nerve activity and arterial pressure.},
  author={Karie E. Scrogin and Eugene T Grygielko and Victoria L Brooks},
  journal={The American journal of physiology},
  year={1999},
  volume={276 6 Pt 2},
  pages={R1579-86}
}
Acute infusion of hypertonic fluid increases mean arterial pressure (MAP) in part by elevating nonrenal sympathetic activity. However, it is not known whether chronic, physiological increases in osmolality also increase sympathetic activity. To test this hypothesis, MAP, heart rate (HR), and lumbar sympathetic nerve activity (LSNA) were measured in conscious, 48-h water-deprived rats (WD) during a progressive reduction in osmolality produced by a 2-h systemic infusion (0.12 ml/min) of 5… CONTINUE READING
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