Oscillopsia: causes and management.

@article{Tilikete2011OscillopsiaCA,
  title={Oscillopsia: causes and management.},
  author={Caroline Tilikete and A. Vighetto},
  journal={Current opinion in neurology},
  year={2011},
  volume={24 1},
  pages={
          38-43
        }
}
PURPOSE OF REVIEW Oscillopsia is an illusion of an unstable visual world. It is associated with poor visual acuity and is a disabling and distressing condition reported by numerous patients with neurological disorders. The goal of this study is to review the recent findings in the various pathophysiological mechanisms of oscillopsia and the potential treatments available. RECENT FINDINGS Oscillopsia most often results from abnormal eye movements or from impaired vestibulo-ocular reflex. A… 
View on PubMed
doi.org
38 Citations
Highly Influential Citations
2
Background Citations
15
Results Citations
1

38 Citations

Central Visual Oscillopsia: Case Report and Review of the Literature
TLDR
The patient’s reported improvement in large- but not small-amplitude oscillopsia suggests that these symptoms may result from different neurophysiological mechanisms, and an experimental intervention using repetitive transcranial magnetic stimulation did not result in clinically significant improvement.
Perceptual Postural Imbalance and Visual Vertigo
TLDR
The effect of visual neglect on posture and balance, even in the absence of a demonstrable visual field defect, has been characterized quantitatively through gait analysis and validates the potential therapeutic value of prism treatment in some patients.
Hallucinatory palinopsia and paroxysmal oscillopsia as initial manifestations of sporadic Creutzfeldt-Jakob disease: A case study
Nystagmus and Saccadic Intrusions.
TLDR
Accurate recognition of nystagmus and saccadic intrusions, including familiarity with the subtleties of examination techniques that allow such eye movements to be unmasked, is critical to proper diagnosis and ultimate alleviation of the visual impairment these patients experience.
Oscillopsia following orbitotomy for intracranial tumor resection
TLDR
Oscillopsia is a potential complication following skull base tumor resection about which patients should be aware and may improve with conservative management alone, although the literature describes repair of orbital defects for ocular pulsations in traumatic and with some developmental conditions.
Migrainous Binocular Peripheral Oscillopsia: A typical Persistent Visual Aura Without Infarction
TLDR
It is suggested that this patient’s binocular peripheral oscillopsia represented persistent cortical oscillopsio without nystagmus, as a very rare atypical variant of migraine persistent visual aura without infarction, constitutes a neuro-ophtalmological syndrome, recently validated in a patient with neuromyelitis optica and visual pathways demyelinating lesions.
Otopathology in Idiopathic Dandy’s Syndrome
  • L. M. VianaM. SalvizS. RauchJ. Nadol
  • Medicine
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
  • 2013
TLDR
The temporal bone histopathology in one individual with idiopathic Dandy’s syndrome showed vestibular atelectasis of all three semicircular canals, preservation of normal saccule and utricle, and severe reduction of the neuronal population in Scarpa's ganglion bilaterally.
Oscillopsia associated with pseudoaccommodation in pseudophakia.
TLDR
A 46-year-old woman presented with shaking of vision in both eyes during near fixation after uneventful implantation of a single-piece multifocal posterior chamber IOL in both Eyes.
Gabapentin and Memantine for Treatment of Acquired Pendular Nystagmus: Effects on Visual Outcomes.
  • E. NerrantL. Abouaf C. Tilikete
  • Medicine, Psychology
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • 2019
TLDR
This study demonstrated that both memantine and gabapentin reduce APN, improving functional visual outcomes and Gabapentin showed a better tolerability, suggesting that this agent should be used as a first-line agent for APN.
Vestibular Function in Children with Neurodevelopmental Disorders: A Systematic Review
TLDR
Since vestibular dysfunctions may result in comparable characteristics as found in NDDs, clinicians should be aware of these similarities when establishing the NDD diagnosis.
...
...

References

SHOWING 1-10 OF 69 REFERENCES
[Oscillopsia: pathophysiological mechanisms and treatment].
TLDR
The physiology of the systems subserving stable vision, the various pathophysiological mechanisms of oscillopsia, and the different treatments available are reviewed to suggest that some visuo-perceptive deficits consecutive to temporo-parietal lesions resemble oscillosia and could result from a deficit in elaborating spatial constancy.
Deficient high-acceleration vestibular function in patients with polyneuropathy
TLDR
The finding that two thirds of patients with axonal or demyelinating polyneuropathy showed unilateral or bilateral gain reductions of the horizontal high-acceleration vestibulo-ocular reflex suggests that, in many patients with PNP, the neuropathic process includes the vestibular nerve.
Superior oblique myokymia: efficacy of medical treatment.
Ocular fixation instabilities in motor neurone disease
TLDR
This is the first study to identify abnormalities of fixation in MND and results indicate that ocular fixation instabilities may be a marker of the sub-clinical frontal lobe dysfunction in M ND.
Gaze fixation deficits and their implication in ataxia–telangiectasia
TLDR
Degeneration of cerebellar Purkinje neurons disinhibit the caudal fastigial oculomotor region (FOR) and vestibular nuclei (VN), which can cause nystagmus, including PAN, while disinhibition of FOR can affect saccade generating mechanisms, leading to SWSI and SO.
Measurement of dynamic visual acuity in patients with vestibular areflexia
TLDR
The test is simple and sensitive enough to separate normal subjects from patients suffering from a vestibular loss and there was a good correlation between the objective results and the subjective complaint of oscillopsia.
Vertigo and vestibular abnormalities in spinocerebellar ataxia type 6
Spinocerebellar ataxia type 6 (SCA6) is a calcium channelopathy due to a pathological CAG repeat expansion in CACNL1A4. Patients frequently describe paroxysmal vertigo early in the disease course,…
Upbeat nystagmus from a demyelinating lesion in the caudal pons.
TLDR
Clinicoanatomic correlation in this patient suggests that a lesion of the superior vestibular nucleus and its efferent crossing ventral tegmental tract could be responsible for the primary position upbeat nystagmus.
Superior Canal Dehiscence Syndrome
Superior canal dehiscence syndrome, or Minor’s syndrome, is a recently described disease that results from the absence of bone over the superior semicircular canal which results in the communication…
An exploration of ocular fixation in Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy
TLDR
It is shown that ocular fixation is impaired in patients with parkinsonian conditions and may prove useful as part of an oculomotor profile to aid with the differentiation of parkinsonians conditions.
...
...