Oscillatory properties of guinea-pig inferior olivary neurones and their pharmacological modulation: an in vitro study.

@article{Llins1986OscillatoryPO,
  title={Oscillatory properties of guinea-pig inferior olivary neurones and their pharmacological modulation: an in vitro study.},
  author={Rodolfo Llin{\'a}s and Yosef Yarom},
  journal={The Journal of physiology},
  year={1986},
  volume={376},
  pages={163-82}
}
The oscillatory properties of the membrane potential in inferior olivary neurones were studied in guinea-pig brain-stem slices maintained in vitro. Intracellular double-ramp current injection at frequencies of 1-20 Hz revealed that inferior olivary neurones tend to fire at two preferred frequencies: 3-6 Hz when the cells were actively depolarized (resting potential less than -50 mV), and 9-12 Hz when they were actively hyperpolarized (resting potential more than -75 mV). In 10% of the… CONTINUE READING
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