Oscillatory control of Delta-like1 in somitogenesis and neurogenesis: A unified model for different oscillatory dynamics.

@article{Shimojo2016OscillatoryCO,
  title={Oscillatory control of Delta-like1 in somitogenesis and neurogenesis: A unified model for different oscillatory dynamics.},
  author={Hiromi Shimojo and Ryoichiro Kageyama},
  journal={Seminars in cell & developmental biology},
  year={2016},
  volume={49},
  pages={76-82}
}
During somite segmentation, mRNA expression of the mouse Notch ligand Delta-like1 (Dll1) oscillates synchronously in the presomitic mesoderm (PSM). However, the dynamics of Dll1 protein expression were rather controversial, and their functional significance was not known. Recent live-imaging analysis showed that Dll1 protein expression also oscillates… CONTINUE READING