Oscillatory Activity in Basal Ganglia and Motor Cortex in an Awake Behaving Rodent Model of Parkinson's Disease.

@article{Delaville2014OscillatoryAI,
  title={Oscillatory Activity in Basal Ganglia and Motor Cortex in an Awake Behaving Rodent Model of Parkinson's Disease.},
  author={Claire Delaville and Ana V. Cruz and Alex McCoy and Elena Brazhnik and Irene Avila and Nikolay Novikov and Judith R. Walters},
  journal={Basal ganglia},
  year={2014},
  volume={3 4},
  pages={221-227}
}
Exaggerated beta range (15-30 Hz) oscillatory activity is observed in the basal ganglia of Parkinson's disease (PD) patients during implantation of deep brain stimulation electrodes. This activity has been hypothesized to contribute to motor dysfunction in PD patients. However, it remains unclear how these oscillations develop and how motor circuits become entrained into a state of increased synchronization in this frequency range after loss of dopamine. It is also unclear whether this increase… CONTINUE READING
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