Oscillations of IgM antibody affinity at the level of single immunocytes.

Abstract

IgM antibody affinity was measured by hemolytic plaque inhibition assays on spleen cells from mice immunized with a single injection of DNP-dextran. Maturation of affinity was found to occur with time after 1 to 1000 microgram of immunogen and to be characterized by rapid oscillations independent from changes inFC number/spleen and in antibody secretion… (More)

Topics

Cite this paper

@article{Pini1980OscillationsOI, title={Oscillations of IgM antibody affinity at the level of single immunocytes.}, author={Cecilia M Pini and Gabriella Di Felice and Renato Baranona Neri and C. Mancini and Giulia Vicari and G. Doria}, journal={Journal of immunology}, year={1980}, volume={125 3}, pages={1349-54} }