Orthostatic hypotension in aging humans.

@article{Shi2000OrthostaticHI,
  title={Orthostatic hypotension in aging humans.},
  author={Xiangrong Shi and D Walter Wray and Kevin J Formes and Hong Wang and Philip M Hayes and Albert H O-Yurvati and Martin S Weiss and Imke Reese},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2000},
  volume={279 4},
  pages={H1548-54}
}
We tested the hypothesis that hypotension occurred in older adults at the onset of orthostatic challenge as a result of vagal dysfunction. Responses of heart rate (HR) and mean arterial pressure (MAP) were compared between 10 healthy older and younger adults during onset and sustained lower body negative pressure (LBNP). A younger group was also assessed after blockade of the parasympathetic nervous system with the use of atropine or glycopyrrolate and after blockade of the beta(1)-adrenoceptor… CONTINUE READING

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