Orthology relations, symbolic ultrametrics, and cographs.

@article{Hellmuth2013OrthologyRS,
  title={Orthology relations, symbolic ultrametrics, and cographs.},
  author={Marc Hellmuth and Maribel Hernandez-Rosales and Katharina T. Huber and Vincent Moulton and Peter F. Stadler and Nicolas Wieseke},
  journal={Journal of mathematical biology},
  year={2013},
  volume={66 1-2},
  pages={399-420}
}
Orthology detection is an important problem in comparative and evolutionary genomics and, consequently, a variety of orthology detection methods have been devised in recent years. Although many of these methods are dependent on generating gene and/or species trees, it has been shown that orthology can be estimated at acceptable levels of accuracy without having to infer gene trees and/or reconciling gene trees with species trees. Thus, it is of interest to understand how much information about… CONTINUE READING

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