Orofacial somatomotor responses in the macaque monkey homologue of Broca's area

  title={Orofacial somatomotor responses in the macaque monkey homologue of Broca's area},
  author={Michael Petrides and Genevi{\`e}ve Cadoret and Scott Mackey},
In the ventrolateral frontal lobe of the human brain there is a distinct entity, cytoarchitectonic area 44 (Broca's area), which is crucial in speech production. There has been controversy over whether monkeys possess an area comparable to human area 44. We have addressed this question in the macaque monkey by combining quantitative architectonic analysis of the cortical areas within the ventrolateral frontal region with electrophysiological recording of neuron activity and electrical… 

Cortico-cortical connections of areas 44 and 45B in the macaque monkey

The mirror neuron system and the strange case of Broca's area

The results show that Broca's area is minimally involved in action observation and has no motor output on hand or phonoarticulatory muscles, challenging its inclusion in the Mirror Neuron System, suggesting that the MNS may be involved in the representation of articulatory rather than semantic components of speech.

Distinct Parietal and Temporal Connectivity Profiles of Ventrolateral Frontal Areas Involved in Language Production

A resting-state functional connectivity study provides a major improvement in understanding the connectivity of the areas in the ventrolateral frontal region that are involved in language production.

Communicative Signaling Activates ‘Broca's’ Homolog in Chimpanzees

Corticostriatal Projections of Macaque Area 44

The role of area 44 as an interface between motor and non-motor functional domains, possibly facilitated by rostral and caudal area 44 subregions with distinct corticostriatal connectivity profiles, is supported.

Distinct neural networks for the volitional control of vocal and manual actions in the monkey homologue of Broca's area

It is suggested that the primate inferior frontal cortex controls the initiation of volitional utterances via a dedicated network of vocal selective neurons that might have been exploited during the evolution of Broca’s area.

The Ventrolateral Frontal Region

Architectonics and cortical connections of the ventral premotor area F5 of the macaque

The present data, together with functional data available in the literature, suggest that the three rostral PMv areas F5p, F5a, andF5a are likely to be architectonically distinct areas, which lie within the postarcuate bank at different antero-posterior levels.

A larynx area in the human motor cortex.

Converging evidence suggests that this area is the principal vocal center of the human motor cortex, and the location of this larynx area is strikingly different from that reported in the monkey.



Reevaluation of ipsilateral corticocortical inputs to the orofacial region of the primary motor cortex in the macaque monkey

The functional diversity of the cortical areas related to orofacial motor behavior and the somatotopical organization in the premotor areas of the frontal cortex are discussed.

Variability of Broca's area homologue in African great apes: implications for language evolution.

It is concluded that gross morphologic patterns do not offer substantive landmarks for the measurement of Brodmann's area 44 in great apes, and whether or not Broca's area homologue of great apes exhibits humanlike asymmetry can only be resolved through further analyses of microstructural components.

Functionally defined smooth and saccadic eye movement subregions in the frontal eye field of Cebus monkeys.

It is proposed that the smooth eye movement subregion in Cebus monkeys may be comparable with the one described in macaque monkeys, and the existence of two subregions of the FEF was further confirmed by single-unit recording results.

Premotor cortex and the recognition of motor actions.

Frontal eye field as defined by intracortical microstimulation in squirrel monkeys, owl monkeys, and macaque monkeys: I. Subcortical connections

Connections that account for the parallel influence of the superior colliculus and the frontal eye field on visuomotor function are revealed and suggest that there has been little evolutionary change in subcortical connections of the frontal eyes fields since the time that these lines of primates diverged.

Afferent and efferent projections of the inferior area 6 in the macaque monkey

This study traced the afferent and efferent connections of the inferior region of area 6 by injecting small amounts of wheat germ agglutinin conjugated to horseradish peroxidase and fluorescent tracers into restricted parts of inferior area 6 and in physiologically determined fields of area 4.

Broca's region revisited: Cytoarchitecture and intersubject variability

These morphologic asymmetries of area 44 provide a putative correlate of the functional lateralization of speech production and show that macroscopic features are not reliable landmarks of cytoarchitectonic borders.

The Mid-ventrolateral Prefrontal Cortex and Active Mnemonic Retrieval

  • M. Petrides
  • Psychology, Biology
    Neurobiology of Learning and Memory
  • 2002
It is argued that the mid-ventrolateral prefrontal cortex is involved in the active retrieval of information from posterior cortical association areas and increases in activity in theMid-dorsolateral region of the frontal cortex occur when the performance of the tasks requires monitoring of information in memory.