Origins of the human genome project

@article{Watson1991OriginsOT,
  title={Origins of the human genome project},
  author={James D. Watson and Robert M Cook-Deegan},
  journal={The FASEB Journal},
  year={1991},
  volume={5},
  pages={11 - 8}
}
The Human Genome Project has become a reality. Building on a debate that dates back to 1985, several genome projects are now in full stride around the world, and more are likely to form in the next several years. Italy began its genome program in 1987, and the United Kingdom and U.S.S.R in 1988. The European communities mounted several genome projects on yeast, bacteria, Drosophila, and Arabidospis thaliana (a rapidly growing plant with a small genome) in 1988, and in 1990 commenced a new 2… 
The human genome project
TLDR
The Human Genome Project (HGP) has matured rapidly and is producing results of great significance.
Aftermath of the Human Genome Project: an era of struggle and discovery
TLDR
Current genomic-era milestones present a unique opportunity to view scientific advance in a thoughtful light, lacing together discoveries, history, and ethical questions, while encouraging the public to consider the varied facets of this scientific evolution with the same curiosity and enthusiasm as the trailblazers of the Human Genome Project.
Primer on medical genomics part I: History of genetics and sequencing of the human genome.
TLDR
The history of genetics is provided, spanning from humankind's initial attempts to understand and influence heredity, to the early scientific work in the field of genetics, and subsequently to the advancements in modern genetics.
The human genome project genetic and physical mapping
  • P. Rosteck
  • Biology
    Trends in Endocrinology & Metabolism
  • 1994
The human genome project Genetic and physical mapping.
  • P. Rosteck
  • Biology
    Trends in cardiovascular medicine
  • 1994
Towards a Drosophila genome map.
A review of current large‐scale mouse knockout efforts
TLDR
The knockout mouse project (KOMP) and the international gene trap consortium (IGTC) were initiated to create convenient resources for scientific research worldwide and knock out all the mouse genes.
The International Human Genome Project
  • E. Birney
  • Engineering, Biology
    Human molecular genetics
  • 2021
Abstract The human genome project was conceived and executed as an international project, due to both pragmatic and principled reasons. This internationality has served the project well, with the
Exuberant Innovation: The Human Genome Project
We present a detailed synthesis of the development of the Human Genome Project (HGP) from 1986 to 2003 in order to test the “social bubble” hypothesis that strong social interactions between
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 26 REFERENCES
Mapping Our Genes: Genome Projects: How Big, How Fast?
ABSTRACT Few scientific projects have excited the imagination or generated the controversies that are associated with the effort to map the human genome. Comprehensive studies of a human genome
A turning point in cancer research: sequencing the human genome.
been made by using model systems of limited complexity, such as cancer cells in vitro and oncogenic viruses. The use of cell cultures avoided the complexity of the whole animal but not the complexity
Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
TLDR
A new basis for the construction of a genetic linkage map of the human genome is described, to develop, by recombinant DNA techniques, random single-copy DNA probes capable of detecting DNA sequence polymorphisms, when hybridized to restriction digests of an individual's DNA.
Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.
TLDR
A thermostable DNA polymerase was used in an in vitro DNA amplification procedure, the polymerase chain reaction, which significantly improves the specificity, yield, sensitivity, and length of products that can be amplified.
Fluorescence detection in automated DNA sequence analysis
TLDR
A method for the partial automation of DNA sequence analysis by means of a fluorophore covalently attached to the oligonucleotide primer used in enzymaticDNA sequence analysis.
A polymorphic DNA marker genetically linked to Huntington's disease
TLDR
The chromosomal localization of the Huntington's disease gene is the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder.
Background on the Human Genome Project (Red Latinoamericana de Ciencias Biologicas 1988); Jorge E.Allende, A View from the South, 5 FASEB J
  • 1991
The Human Genome Project.
...
1
2
3
...