Origins of secondary metabolism.

@article{Cavaliersmith1992OriginsOS,
  title={Origins of secondary metabolism.},
  author={T Cavalier-smith},
  journal={Ciba Foundation symposium},
  year={1992},
  volume={171},
  pages={64-80; discussion 80-7}
}
Secondary metabolites generally benefit their producers as poisons that protect them against competitors, predators or parasites. They are produced from universally present precursors (most often acetyl-CoA, amino acids or shikimate) by specific enzymes that probably arose by the duplication and divergence of genes originally coding for primary metabolism. Most secondary metabolites are restricted to single major taxa on the universal phylogenetic tree and so probably originated only once. But… CONTINUE READING
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