Origins of life: Systems chemistry on early Earth

@article{Szostak2009OriginsOL,
  title={Origins of life: Systems chemistry on early Earth},
  author={Jack W. Szostak},
  journal={Nature},
  year={2009},
  volume={459},
  pages={171-172}
}
Understanding how life emerged on Earth is one of the greatest challenges facing modern chemistry. A new way of looking at the synthesis of RNA sidesteps a thorny problem in the field. 
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Reactivity and selectivity in photochemical prebiotic synthesis are discussed, as are their implications for origins of life scenarios and their plausibility, and the future directions of this research.
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The coevolutionary emergence from a communal system at the common root can most naturally explain the vast discrepancy in subcellular organization between modern eukaryotes on the one hand and both archaea and bacteria on the other.
Chemistry of Abiotic Nucleotide Synthesis.
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This review provides a background and up-to-date progress that will allow the reader to judge where the field stands currently and what remains to be achieved, and concludes with a cautionary note about coming to conclusions about whether the problem of chemistry of prebiotic nucleotide synthesis has been solved.
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The task to understand life's origin as a rational process is closely related to the earlier attempts of the present author to design and construct supra-molecular machines and the approach given here is an attempt.
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An extended version of the AHV scenario is put forward which enhances the conformity between extant life and its earliest progenitor by extensively making use of fougerite's mechanistic and catalytic particularities.
Conversion of Biosynthetic Precursors of RNA to Those of DNA by Photoredox Chemistry
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DNA biosynthetic precursors can be formed abiotically from those of RNA allowing for an early evolutionary transition to life based on RNA and DNA.
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RNA world