Origins of binary gene expression in post-transcriptional regulation by microRNAs

  title={Origins of binary gene expression in post-transcriptional regulation by microRNAs},
  author={I Bose and Sumana Ghosh},
  journal={The European Physical Journal E},
  • I. Bose, S. Ghosh
  • Published 2 May 2012
  • Biology
  • The European Physical Journal E
AbstractMicroRNA-mediated regulation of gene expression is characterised by some distinctive features that set it apart from unregulated and transcription-factor-regulated gene expression. Recently, a mathematical model has been proposed to describe the dynamics of post-transcriptional regulation by microRNAs. The model explains the observations made in single-cell experiments quite well. In this paper, we introduce some additional features into the model and consider two specific cases. In the… 
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