Origins and functional evolution of Y chromosomes across mammals

@article{Cortez2014OriginsAF,
  title={Origins and functional evolution of Y chromosomes across mammals},
  author={Diego Cortez and Ray Marin and Deborah Toledo-Flores and Laure Froidevaux and Ang{\'e}lica Liechti and Paul D. Waters and Frank Gr{\"u}tzner and Henrik Kaessmann},
  journal={Nature},
  year={2014},
  volume={508},
  pages={488-493}
}
Y chromosomes underlie sex determination in mammals, but their repeat-rich nature has hampered sequencing and associated evolutionary studies. Here we trace Y evolution across 15 representative mammals on the basis of high-throughput genome and transcriptome sequencing. We uncover three independent sex chromosome originations in mammals and birds (the outgroup). The original placental and marsupial (therian) Y, containing the sex-determining gene SRY, emerged in the therian ancestor… 
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