Original research paper. Characterization and taste masking evaluation of microparticles with cetirizine dihydrochloride and methacrylate-based copolymer obtained by spray drying.

@article{Amelian2017OriginalRP,
  title={Original research paper. Characterization and taste masking evaluation of microparticles with cetirizine dihydrochloride and methacrylate-based copolymer obtained by spray drying.},
  author={Aleksandra Amelian and Marta Szekalska and Patrycja Ciosek and Anna Basa and Katarzyna Winnicka},
  journal={Acta pharmaceutica},
  year={2017},
  volume={67 1},
  pages={
          113-124
        }
}
Taste of a pharmaceutical formulation is an important parameter for the effectiveness of pharmacotherapy. Cetirizine dihydrochloride (CET) is a second-generation antihistamine that is commonly administered in allergy treatment. CET is characterized by extremely bitter taste and it is a great challenge to successfully mask its taste; therefore the goal of this work was to formulate and characterize the microparticles obtained by the spray drying method with CET and poly(butyl methacrylate-co-(2… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

, A . Czajkowska - Kośnik , K . Sosnowska and A . Amelian , Evaluation of alginate microspheres with metronidazole obtained by the spray drying technique

K. Winnicka Szekalska
  • Acta Pol . Pharm . Drug Res .
  • 2015

, P . Axe and J . Breitkreutz , In - vitro and in - vivo evaluation of taste - masked cetirizine hydrochloride formulated in oral lyophilisates

M. Bonnefille Maniruzzaman, A. Aranyos, M. J. Snowden, D. Douroumis
  • Int . J . Pharm .
  • 2015

Quantitative analysis of active pharmaceutical ingredients ( APIs ) using a potentiometric electronic tongue in a SIA flow system

M. T. Goodarzi Ahmadi-Motamayel, H. Abddsamadi S. S. Hendi, N. Rafiean
  • Electroanalysis
  • 2015