Original Research: The Effects of Red Yeast Rice Supplementation on Cholesterol Levels in Adults

@article{Peng2017OriginalRT,
  title={Original Research: The Effects of Red Yeast Rice Supplementation on Cholesterol Levels in Adults},
  author={Diane Peng and Amy Fong and A. van Pelt},
  journal={AJN, American Journal of Nursing},
  year={2017},
  volume={117},
  pages={46–54}
}
&NA; Purpose: Red yeast rice (RYR) supplementation has become a popular alternative to statin therapy in treating hypercholesterolemia. This state-of-the-science review seeks to explore the most recent evidence on the effectiveness and safety of RYR supplementation in treating dyslipidemic adults. Methods: This review extends the time frame of a meta-analysis performed by Li and colleagues in 2014; specifically, we looked at the literature published between September 2013 and April 2016. We… Expand
Medicinal plants in treatment of hypertriglyceridemia: A review based on their mechanisms and effectiveness.
TLDR
It seems that use of these plants as complementary therapeutics or extraction of their active ingredients along with currently available drugs will improve the management of HTg in patients. Expand
Red Yeast Rice: A Systematic Review of the Traditional Uses, Chemistry, Pharmacology, and Quality Control of an Important Chinese Folk Medicine
Red yeast rice (RYR), a Chinese traditional folk medicine produced by the fermentation of cooked rice kernels with a Monascaceae mold, Monascus purpureus, has long been used to treat bloodExpand
A decade of nutraceutical patents: where are we now in 2018?
TLDR
Nutraceuticals represent a challenge for the future of drug-based pharmacotherapy, and, at the same time, are a powerful tool for the prevention of chronic disease. Expand
Regulatory effect of Phikud Navakot extract on HMG-CoA reductase and LDL-R: potential and alternate agents for lowering blood cholesterol
TLDR
The use of Ya-Hom Navakot or PN may provide an alternative treatment to lower cholesterol through HMGCR gene inhibition and LDL-R gene enhancement. Expand
A questionable way to lower cholesterol: food supplements containing red yeast rice to be taken only on medical advice-BfR opinion No 003/2020 issued 15 January 2020
  • 2020
Red “yeast” rice (also known as red rice) has its traditional origin in China. Red yeast rice is made by fermenting boiled white rice with a type of mould of the Monascus genus. This producesExpand
Lipid-lowering agents for concurrent cardiovascular and chronic kidney disease
TLDR
This narrative review discusses the use of hypolipidaemic drugs in patients with both CVD and CKD, and statin±ezetimibe therapy should not be initiated, but should be continued, in dialysis-treated CKD patients. Expand
Screening of gamma-aminobutyric acid-producing lactic acid bacteria and its application in Monascus-fermented rice production.
TLDR
A two-stage fermentation using microbial consortia containing M. anka 20-2 and L. plantarum 8014 was developed for the production of bioactive MFR, in which the active ingredients monacolin K and GABA were simultaneously enriched, with good consumer acceptability due to the aromatic scent produced by lactic acid bacteria. Expand
Assimilation of Cholesterol by Monascus purpureus
TLDR
The results indicate that M. purpureus CBS 109.07 can reduce cholesterol content in vitro and may have a potential application in probiotics. Expand
Update on cardiovascular prevention in clinical practice: A position paper of the European Association of Preventive Cardiology of the European Society of Cardiology*
TLDR
Greater emphasis has been put on a population-based approach and on disease-specific interventions, avoiding re-interpretation of information already and previously considered. Expand
Pigments from Filamentous Ascomycetes for Combination Therapy.
TLDR
This review summarizes and discusses the general principles of this approach, introduced and supported by numerous examples, and the prediction of the future potential application of this methodology is included. Expand
...
1
2
...

References

SHOWING 1-10 OF 41 REFERENCES
Traditional Chinese lipid-lowering agent red yeast rice results in significant LDL reduction but safety is uncertain - a systematic review and meta-analysis.
TLDR
Only when the mild profile of adverse reactions can be affirmed in studies with adequate methodology for safety assessment, RYR might be a safe and effective treatment option for dyslipidemia and cardiovascular risk reduction in statin intolerant patients. Expand
A Meta-Analysis of Red Yeast Rice: An Effective and Relatively Safe Alternative Approach for Dyslipidemia
TLDR
It is suggested that further long-term, rigorously designed randomized controlled trials are still warranted before red yeast rice could be recommended to patients with dyslipidemia, especially as an alternative to statins. Expand
Red yeast rice lowers cholesterol in physicians - a double blind, placebo controlled randomized trial
TLDR
The RYR formulation under study was effective in lowering cholesterol and LDL cholesterol in this study population and resulted in lower cardiovascular risk as measured with SCORE (Systematic COronary Risk Evaluation). Expand
Chinese red yeast rice (Monascus purpureus) for primary hyperlipidemia: a meta-analysis of randomized controlled trials
TLDR
Current evidence shows short-term beneficial effects of RYR preparations on lipid modification, but more rigorous trials are needed, and long-term effects and safety should be investigated if RYP preparations are to be recommended as one of the alternative treatments for primary hyperlipidemia. Expand
A combined natural supplement lowers LDL cholesterol in subjects with moderate untreated hypercholesterolemia: a randomized placebo-controlled trial
TLDR
The NCLS was effective in reducing low-density lipoprotein cholesterol and apolipoprotein B100 in subjects with moderate hypercholesterolemia, without modifying safety parameters. Expand
ESSENS dyslipidemia: A placebo-controlled, randomized study of a nutritional supplement containing red yeast rice in subjects with newly diagnosed dyslipidemia.
TLDR
This study demonstrates the efficacy and safety of RYR-NS in lowering LDL-C and non-HDL-C after 12 wk, with magnitude of cholesterol reduction being comparable to that seen with moderate-intensity statin therapy. Expand
Red Yeast Rice for the Treatment of Dyslipidemia
TLDR
Red yeast rice (RYR) is a Chinese herbal supplement produced by fermenting white rice with the yeast, Monascus purpureus, which contains a variety of monacolins, which inhibit hydroxymethylglutaryl-coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. Expand
Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement.
TLDR
Red yeast rice significantly reduces total cholesterol, LDL cholesterol, and total triacylglycerol concentrations compared with placebo and provides a new, novel, food-based approach to lowering cholesterol in the general population. Expand
Effect of red yeast rice combined with antioxidants on lipid pattern, hs-CRP level, and endothelial function in moderately hypercholesterolemic subjects
TLDR
It is demonstrated that a 10 mg monacolin nutraceutical treatment appears to safely reduce cholesterolemia, hs-CRP, and markers of vascular remodeling in moderately hypercholesterolemic subjects, and results need to be confirmed in larger patient samples and in studies with longer duration. Expand
Testing the Short-Term Efficacy of a Lipid-Lowering Nutraceutical in the Setting of Clinical Practice: A Multicenter Study
TLDR
In the short term, a combined nutraceutical containing red yeast rice and PUFAs is well tolerated and efficacious in reducing plasma lipid levels in subjects affected by primary polygenic hypercholesterolemia and metabolic syndrome. Expand
...
1
2
3
4
5
...