Original Article: Highly conserved cross‐reactive CD4+ T‐cell HA‐epitopes of seasonal and the 2009 pandemic influenza viruses

@inproceedings{Duvvuri2010OriginalAH,
  title={Original Article: Highly conserved cross‐reactive CD4+ T‐cell HA‐epitopes of seasonal and the 2009 pandemic influenza viruses},
  author={Venkata R Duvvuri and Seyed M. Moghadas and Hongbin Guo and Bhargavi Duvvuri and Jane Marie Heffernan and David N. Fisman and Gillian Wu and Jianhong Wu},
  booktitle={Influenza and other respiratory viruses},
  year={2010}
}
BACKGROUND The relatively mild nature of the 2009 influenza pandemic (nH1N1) highlights the overriding importance of pre-existing immune memory. The absence of cross-reactive antibodies to nH1N1 in most individuals suggests that such attenuation may be attributed to pre-existing cellular immune responses to epitopes shared between nH1N1 virus and previously circulating strains of inter-pandemic influenza A viruses. RESULTS We sought to identify potential CD4+ T cell epitopes and predict the… CONTINUE READING

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