Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen.

@article{Brinkmann2000OriginOR,
  title={Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen.},
  author={Ralf Brinkmann and Gereon Huettmann and Jan Roegener and Johann B Roider and Reginald Birngruber and Charles P. Lin},
  journal={Lasers in surgery and medicine},
  year={2000},
  volume={27 5},
  pages={451-64}
}
BACKGROUND AND OBJECTIVE Selective photodamage of the retinal pigment epithelium (RPE) is a new technique to treat a variety of retinal diseases without causing adverse effects to surrounding tissues such as the neural retina including the photoreceptors and the choroid. In this study, the mechanism of cell damage after laser irradiation was investigated. STUDY DESIGN/MATERIALS AND METHODS Single porcine RPE-melanosomes and RPE cells were irradiated with a Nd:YLF laser (wavelength lambda… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 72 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Thermal modeling in biological tissue

  • R. Birngruber
  • 1980
Highly Influential
5 Excerpts

Multiple pulse thresholds in live eyes for ultrashort laser pulses in the near-infrared

  • DJ Stolarski, CP Cain, CA Toth, GD Noojin, BA. Rockwell
  • Proc SPIE
  • 1999
2 Excerpts

Selective cell killing by microparticle absorption of pulsed laser radiation

  • CP Lin, MW Kelly, SAB Sibayan, MA Latina, RR. Anderson
  • IEEE J Select Top Quant Elect 1999;5:963–968
  • 1999
1 Excerpt

Cavitation and acoustic emission around laser-heated microparticles

  • CP Lin, MW Kelly
  • Appl Phys Lett
  • 1998
3 Excerpts

Control and detection of subthreshold effects in the first clinical trial of macular diseases

  • J Roider, C Wirbelauer, R Brinkmann, H Laqua, R. Birngruber
  • Inv Ophthalmol Vis Sci 1998;39:104
  • 1998
1 Excerpt

Similar Papers

Loading similar papers…