Origin of life: The RNA world

@article{Gilbert1986OriginOL,
  title={Origin of life: The RNA world},
  author={Walter Gilbert},
  journal={Nature},
  year={1986},
  volume={319},
  pages={618-618}
}
Sur la base de la decouverte d'activites enzymatiques de certains ARN (chez E. coli au cours de la maturation des ARN+ et chez Tetrahymena avec un exon d'un ARNr a auto-epissage), l'auteur postule un systeme, auto-replicatif a l'origine uniquement compose de molecules d'ARN 
A new paradigm for the folding of ribonucleic acids
De recentes decouvertes montrent le role important que joue l’acide ribonucleique (ARN) au sein des cellules, que ce soit le controle de l’expression genetique, la regulation de plusieurs processus
On the dimerization of the primitive tRNAs: implications in the origin of genetic code.
TLDR
A structural model for the first aminoacyl-tRNA synthetase consisting of an RNA complex formed between two primitive tRNA molecules through two intermolecular loop-strand interactions is proposed, with implications in the origin of the genetic code.
RNA evolution and the origins of life
TLDR
It is doubtful that life began with RNA, but consideration of what came before RNA must take into account relevant information from geochemistry, prebiotic chemistry and nucleic acid biochemistry.
RNA catalysis and the origins of life.
  • L. Orgel
  • Biology, Chemistry
    Journal of theoretical biology
  • 1986
Catalytic RNA and the origin of genetic systems.
The RNA World as a Model System to Study the Origin of Life
Chemical origins of life: Prebiotic RNA unstuck.
TLDR
Two separate studies focusing on RNA's backbone connectivity offer partial solutions to some of the problems raised with this hypothesis for the origin of life.
Exiting an RNA world
The RNA world hypothesis gains support from the in vitro evolution of a bifunctional ribozyme that can recognize an activated glutaminyl ester and subsequently aminoacylate a tRNA molecule.
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