Origin of intracellular lumina in HT 29 colonic adenocarcinoma cell line. An ultrastructural study.


When glucose is added to the culture medium, some cells of the undifferentiated HT 29 line derived from a human colonic adenocarcinoma develop spherical structures which are bordered with microvilli and contain osmiophilic substance. These lumina, demonstrated as intracellular by the Ruthenium red method, in a preceeding paper, seem to originate from… (More)