Origin of Microcells in the Human Sarcoma Cell Line HT-1080

  title={Origin of Microcells in the Human Sarcoma Cell Line HT-1080},
  author={Indulis Buiķis and Līga Harju and Talivaldis Freivalds},
  booktitle={Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology},
The aim of this study was to investigate the development of microcells in the human sarcoma cell line HT-1080 after interference with thiophosphamidum. We found that damaged interphase macrocells located at the projection of the nucleolus may form one or several microcells. The micronuclei of the microcells intensively incorporate the thymidine analogue 5-bromo-2'-deoxyuridine and strongly express argyrophilic nucleolar organiser region proteins. At an early phase of the development, the… CONTINUE READING


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