Origin of Metazoa: Sponges as Living Fossils

  title={Origin of Metazoa: Sponges as Living Fossils},
  author={Werner E. G. M{\"u}ller},
  • W. Müller
  • Published 1998
  • Biology
  • Naturwissenschaften
Geodia cydonium, which code for proteins. The analyses of their deduced amino acid sequences allowed a molecular biological approach to solve the problem of monophyly of Metazoa. Molecules of the extracellular matrix/basal lamina, with the integrin receptor, fibronectin, and galectin as prominent examples, cell-surface receptors (tyrosine kinase receptor), elements of sensory systems (crystallin, metabotropic glutamate receptor), and homologs/modules of an immune system (immunoglobulin like… 

Review: How was metazoan threshold crossed? The hypothetical Urmetazoa.

  • W. Müller
  • Biology
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology
  • 2001

Towards an understanding of the molecular basis of immune responses in sponges: The marine demosponge Geodia cydonium as a model

The adhesion molecules presumably involved in the sponge immune system are reviewed and it is reported that in the model sponge system of G. cydonium, allogeneic rejection involves an upregulation of phenylalanine hydroxylase, an enzyme initiating the pathway to melanin synthesis.

Molecular Evolution of the Metazoan Extracellular Matrix: Cloning and Expression of Structural Proteins from the Demosponges Suberites domuncula and Geodia cydonium

The ligand for one of the autopomorphic characters of Metazoa, the single-transmembrane receptor protein with the receptor tyrosine kinase (RTK) from G. cydonium, is identified and it is documented that expression of the fibrous ECM molecule collagen is regulated by the characteristic metazoan morphogens myotrophin and endothelial monocyte-activating polypeptide.

Receptor tyrosine kinase, an autapomorphic character of metazoa: identification in marine sponges.

It is concluded that the RTK molecules have evolved in sponge prior to the "Cambrian Explosion" and have contributed to the rapid appearance of the higher metazoan phyla and that sponges are, as a taxon, also monophyletic.

The significance of sponges for comparative studies of developmental evolution

It is argued that sponges strike a different balance between patterning and plasticity than other animals, and that environmental inputs may have prominence over genetically regulated developmental mechanisms.

Porifera : an enigmatic taxon disclosed by molecular biology / cell biology

From the insights into the genome repertoire of some representative species within the Porifera it became overt that the ancestor of all multicellular animals, the Urmetazoa, was provided with a surprisingly high complexity of structural and regulatory molecules.

Phylogenetic position of sponges in early metazoan evolution and bionic applications of siliceous sponge spicules

The emergence of sponge, evolutionary novelties found in sponges, and the phylogenetic position of spongees in early metazoan evolution are highlighted, including the involvement of other molecules in silica metabolism and their potential application in nanobiotechnology and medicine are given.



Experimental Indication in Favor of the Introns-Late Theory: The Receptor Tyrosine Kinase Gene from the Sponge Geodia cydonium

The results support the view that ancient genes were not ``in pieces,'' and assume that introns were inserted into these genes after splitting off the sponge taxa from other metazoan organisms over 600 million years ago.

The Early Evolution of Metazoa and the Significance of Problematic Taxa

The Origin of metazoans: a phylogeny deducted from sequences of the 28S ribosomal RNA and problems of arthropod phylogeny with some notes on taxa of doubtful affinities, and a new approach to analyzing problematica.

Guidebook to the extracellular matrix, anchor, and adhesion proteins

This new edition of Guidebook to the Extracellular Matrix and Adhesion Proteins brings up-to-date information on the purification, activities, antibodies and genes for the proteins found in the

Protein Evolution by Exon-Shuffling

This text surveys evidence for modular protein evolution by exon-shuffling and lists the proteins that clearly evolved by this mechanism and the principles and mechanism of this process.

The Origin and Early Evolution of Metazoa

A generally conical cutting head for an underwater dredger includes a plurality of helical cutting arms having teeth mounted thereon that removes a symmetrical piece of soil and is not subjected to loads parallel to the local section of the contour line.

The origin and early evolution of animals

Find the secret to improve the quality of life by reading this origin and early evolution of animals, which can be your favorite book to read after having this book.

Origin and evolution of the elements

This work on the origin and evolution of cosmic elements draws upon the work of experts at an international conference held in Paris in 1992. It deals with stellar and primordial nuceosynthesis,

The adhesion molecule factsbook

The Invertebrates: Protozoa Through Ctenophora