Origin of Gliomas.

@article{Cahill2018OriginOG,
  title={Origin of Gliomas.},
  author={Daniel P Cahill and Sevin Turcan},
  journal={Seminars in neurology},
  year={2018},
  volume={38 1},
  pages={5-10}
}
Malignant glioma is a common type of brain tumor that remains largely incurable. Although a definitive cell of origin of gliomas remains elusive, numerous population studies, sequencing efforts, and genetically engineered mouse models have contributed to our understanding of the early events that may lead to gliomagenesis. Herein we summarize our current knowledge on the population epidemiology of gliomas, heritable genetic risk factors, the somatic events that contribute to tumor evolution… CONTINUE READING
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