Origin and physiological roles of inflammation

@article{Medzhitov2008OriginAP,
  title={Origin and physiological roles of inflammation},
  author={Ruslan Medzhitov},
  journal={Nature},
  year={2008},
  volume={454},
  pages={428-435}
}
Inflammation underlies a wide variety of physiological and pathological processes. Although the pathological aspects of many types of inflammation are well appreciated, their physiological functions are mostly unknown. The classic instigators of inflammation — infection and tissue injury — are at one end of a large range of adverse conditions that induce inflammation, and they trigger the recruitment of leukocytes and plasma proteins to the affected tissue site. Tissue stress or malfunction… 
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