Origin and evolution of the vertebrate leukocyte receptors: the lesson from tunicates

@article{Zucchetti2009OriginAE,
  title={Origin and evolution of the vertebrate leukocyte receptors: the lesson from tunicates},
  author={Ivana Zucchetti and Rosaria De Santis and Simona Grusea and Pierre Pontarotti and Louis du Pasquier},
  journal={Immunogenetics},
  year={2009},
  volume={61},
  pages={463-481}
}
Two selected receptor genes of the immunoglobulin superfamily (IgSF), one CTX/JAM family member, and one poliovirus receptor-like nectin that have features of adhesion molecules can be expressed by Ciona hemocytes, the effectors of immunity. They can also be expressed in the nervous system (CTX/JAM) and in the ovary (nectin). The genes encoding these receptors are located among one set of genes, spread over Ciona chromosomes 4 and 10, and containing other IgSF members homologous to those… CONTINUE READING

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