Origin and evolution of the enhancer of split complex

  title={Origin and evolution of the enhancer of split complex},
  author={P K Dearden},
  booktitle={BMC Genomics},
The Enhancer of split complex is an unusual gene complex found in Arthropod genomes. Where known this complex of genes is often regulated by Notch cell signalling and is critically important for neurogenesis. The Enhancer of split complex is made up of two different classes of genes, basic helix-loop-helix-orange domain transcription factors and bearded class genes. The association of these genes has been detected in the genomes of insects and crustaceans. Tracing the evolution of the Enhancer… CONTINUE READING
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