Origin and evolution of laminin gene family diversity.

@article{Fahey2012OriginAE,
  title={Origin and evolution of laminin gene family diversity.},
  author={Bryony Fahey and Bernard M. Degnan},
  journal={Molecular biology and evolution},
  year={2012},
  volume={29 7},
  pages={1823-36}
}
Laminins are a family of multidomain glycoproteins that are important contributors to the structure of metazoan extracellular matrices. To investigate the origin and evolution of the laminin family, we characterized the full complement of laminin-related genes in the genome of the sponge, Amphimedon queenslandica. As a representative of the Demospongiae, a group consistently placed within the earliest diverging branch of animals by molecular phylogenies, Amphimedon is uniquely placed to provide… CONTINUE READING
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