Origin and characterization of alpha smooth muscle actin-positive cells during murine lung development.

@article{Moiseenko2017OriginAC,
  title={Origin and characterization of alpha smooth muscle actin-positive cells during murine lung development.},
  author={Alena Moiseenko and Vahid Kheirollahi and Cho-Ming Chao and Negah Ahmadvand and Jennifer Quantius and Jochen Wilhelm and Susanne Herold and Katrin Ahlbrecht and Rory E Morty and Albert A Rizvanov and Parviz Minoo and Elie El Agha and Saverio Bellusci},
  journal={Stem cells},
  year={2017},
  volume={35 6},
  pages={1566-1578}
}
ACTA2 expression identifies pulmonary airway and vascular smooth muscle cells (SMCs) as well as alveolar myofibroblasts (MYF). Mesenchymal progenitors expressing fibroblast growth factor 10 (Fgf10), Wilms tumor 1 (Wt1), or glioma-associated oncogene 1 (Gli1) contribute to SMC formation from early stages of lung development. However, their respective contribution and specificity to the SMC and/or alveolar MYF lineages remain controversial. In addition, the contribution of mesenchymal cells… CONTINUE READING

Similar Papers

Loading similar papers…