Origin and Fate of Erythropoietin in Human Milk

  title={Origin and Fate of Erythropoietin in Human Milk},
  author={Sandra E Juul and Yanru Zhao and J. B. Dame and Yan Du and Alan D. Hutson and Robert D. Christensen},
  journal={Pediatric Research},
Erythropoietin (Epo) is a normal constituent of human milk, but the origin and fate of this cytokine in milk are not known. Regarding its origin, we hypothesized that cells of the mammary gland secrete Epo into milk actively and, therefore, that concentrations in milk do not correlate with concentrations in serum. Regarding its fate, we hypothesized that Epo concentrations in milk change with time postpartum and that Epo in milk is protected from digestion in the neonatal gastrointestinal tract… CONTINUE READING


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The effects of enteral versusparenteral recombinant erythropoietin on bowel growth

  • SE Juul, Y Zhao, C Dame
  • Pediatr Res
  • 2000
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