Origin and Co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat.

@article{Edvinsson2001OriginAC,
  title={Origin and Co-localization of nitric oxide synthase, CGRP, PACAP, and VIP in the cerebral circulation of the rat.},
  author={Lars Edvinsson and Tor B Els{\aa}s and Norio Suzuki and Teruo Shimizu and Tony Jer-Fu Lee},
  journal={Microscopy research and technique},
  year={2001},
  volume={53 3},
  pages={221-8}
}
The origin of perivascular nerve fibres storing nitric oxide synthase (NOS) and co-localisation with perivascular neuropeptides were examined in the rat middle cerebral artery (MCA) by retrograde tracing with True Blue (TB) in combination with immunocytochemistry. Application of TB to the proximal part of the middle cerebral artery labelled nerve cell bodies ipsilaterally in the trigeminal, sphenopalatine, otic, and superior cervical ganglia. A few labelled cell bodies were seen contralaterally… CONTINUE READING

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