Orientia tsutsugamushi, agent of scrub typhus, displays a single metapopulation with maintenance of ancestral haplotypes throughout continental South East Asia.

@article{Wongprompitak2015OrientiaTA,
  title={Orientia tsutsugamushi, agent of scrub typhus, displays a single metapopulation with maintenance of ancestral haplotypes throughout continental South East Asia.},
  author={Patimaporn Wongprompitak and Veasna Duong and Wichittra Anukool and Lay Sreyrath and Trịnh Thị Xuan Mai and Laurent Gavotte and Catherine Moulia and Emmanuel Cornillot and Pattama Ekpo and Yupin Suputtamongkol and Philippe Buchy and Roger Frutos},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2015},
  volume={31},
  pages={1-8}
}
Orientia tsutsugamushi is the causative agent of scrub typhus, a major cause of febrile illness in rural area of Asia-Pacific region. A multi-locus sequence typing (MLST) analysis was performed on strains isolated from human patients from 3 countries in Southeast Asia: Cambodia, Vietnam and Thailand. The phylogeny of the 56-kDa protein encoding gene was analyzed on the same strains and showed a structured topology with genetically distinct clusters. MLST analysis did not lead to the same… CONTINUE READING