Corpus ID: 25047894

Oridonin Induces Apoptosis in Human Nasopharyngeal Carcinoma Cells Involving ROS Generation.

@article{Zhang2017OridoninIA,
  title={Oridonin Induces Apoptosis in Human Nasopharyngeal Carcinoma Cells Involving ROS Generation.},
  author={P. Zhang and S-R Zhao and F. Liu and X. Sun and H. Liu},
  journal={Folia biologica},
  year={2017},
  volume={63 4},
  pages={
          155-163
        }
}
Oridonin, an ent-kaurene diterpenoid isolated from the traditional Chinese herb Rabdosia rubescens, has been reported to be a potent cytotoxic agent against a wide array of cancer cells. However, its effect on human nasopharyngeal carcinoma (NPC) cells has not been well investigated. The present study aimed to explore the anti-tumour effect of oridonin in NPC cells and its underlying mechanisms. Cell viability was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay… Expand
6 Citations
Oridonin protects LPS-induced acute lung injury by modulating Nrf2-mediated oxidative stress and Nrf2-independent NLRP3 and NF-κB pathways
  • 20

References

SHOWING 1-10 OF 38 REFERENCES
Oridonin induces apoptosis, inhibits migration and invasion on highly-metastatic human breast cancer cells.
  • 84
Oridonin phosphate-induced autophagy effectively enhances cell apoptosis of human breast cancer cells
  • 35
Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line
  • 33
  • PDF
Oridonin: targeting programmed cell death pathways as an anti‐tumour agent
  • 45
Oridonin, a promising antitumor natural product in the chemotherapy of hematological malignancies.
  • 21
Effects of G6PD activity inhibition on the viability, ROS generation and mechanical properties of cervical cancer cells.
  • 24
Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics.
  • 115
Oridonin, a Promising ent-Kaurane Diterpenoid Lead Compound
  • 28
  • PDF
...
1
2
3
4
...