Corpus ID: 25047894

Oridonin Induces Apoptosis in Human Nasopharyngeal Carcinoma Cells Involving ROS Generation.

  title={Oridonin Induces Apoptosis in Human Nasopharyngeal Carcinoma Cells Involving ROS Generation.},
  author={P. Zhang and S-R Zhao and F. Liu and X. Sun and H. Liu},
  journal={Folia biologica},
  volume={63 4},
Oridonin, an ent-kaurene diterpenoid isolated from the traditional Chinese herb Rabdosia rubescens, has been reported to be a potent cytotoxic agent against a wide array of cancer cells. However, its effect on human nasopharyngeal carcinoma (NPC) cells has not been well investigated. The present study aimed to explore the anti-tumour effect of oridonin in NPC cells and its underlying mechanisms. Cell viability was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay… Expand
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