Orgaran (Org 10172) or heparin for preventing venous thrombosis after elective surgery for malignant disease? A double-blind, randomised, multicentre comparison. ANZ-Organon Investigators' Group.

@article{Gallus1993Orgaran1,
  title={Orgaran (Org 10172) or heparin for preventing venous thrombosis after elective surgery for malignant disease? A double-blind, randomised, multicentre comparison. ANZ-Organon Investigators' Group.},
  author={Alexander S. Gallus and J. Cade and Paul A Ockelford and Susan Hepburn and Mari{\"e}lle Maas and Harry N. Magnani and Tracey Bucknall and Jennifer L. Airey Laura M. Stevens and F Porteous},
  journal={Thrombosis and haemostasis},
  year={1993},
  volume={70 4},
  pages={562-7}
}
This double-blind, randomised, multicentre trial in 513 patients having elective surgery for intra-abdominal or intrathoracic malignancy compared the efficacy and safety of venous thrombosis (VT) prophylaxis using 750 anti-factor Xa units of Orgaran (a mixture of low molecular weight heparinoids) given subcutaneously (sc) twice-daily with that of twice-daily injections of 5,000 units standard heparin. The main study endpoints were the development of postoperative VT detected by 125I-fibrinogen… CONTINUE READING

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