Organotypic slice culture from human adult ventricular myocardium.

  title={Organotypic slice culture from human adult ventricular myocardium.},
  author={Matthias Brandenburger and Jan Wenzel and Roman Bogdan and Doreen Richardt and Filomain Nguemo and Michael Reppel and J{\"u}rgen Hescheler and Heinrich Terlau and Andreas Dendorfer},
  journal={Cardiovascular research},
  volume={93 1},
AIMS Cardiovascular research requires complex and functionally intact experimental models. Due to major differences in the cellular and subcellular composition of the myocardium between species, the use of human heart tissue is highly desirable. To enhance the experimental use of the human myocardium, we established methods for the preparation of vital tissue slices from the adult ventricular myocardium as well as conditions for their long-term preservation in organotypic culture. METHODS AND… CONTINUE READING


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