Organotin compounds: toxicokinetic aspects.

  title={Organotin compounds: toxicokinetic aspects.},
  author={Klaus Erich Appel},
  journal={Drug metabolism reviews},
  volume={36 3-4},
Organotin compounds have a broad range of applications. While dialkyltin compounds are used primarily as stabilizers for plastics, trisubstituted organotins are mainly used as biocides e.g., as an active ingredient of marine antifouling paints for boats and ships. Since a number of organotin compounds have been demonstrated to be toxic, there is increasing concern that their widespread use may cause adverse effects within environmental and biological systems. Besides carcinogenic and neurotoxic… CONTINUE READING