Organoselenium compounds as mimics of selenoproteins and thiol modifier agents.

Abstract

Selenium is an essential trace element for animals and its role in the chemistry of life relies on a unique functional group: the selenol (-SeH) group. The selenol group participates in critical redox reactions. The antioxidant enzymes glutathione peroxidase (GPx) and thioredoxin reductase (TrxR) exemplify important selenoproteins. The selenol group shares… (More)
DOI: 10.1039/c7mt00083a

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