Organophosphorous pesticide exposure alters sperm chromatin structure in Mexican agricultural workers.

@article{SnchezPea2004OrganophosphorousPE,
  title={Organophosphorous pesticide exposure alters sperm chromatin structure in Mexican agricultural workers.},
  author={Luz Carmen S{\'a}nchez-Pe{\~n}a and Biunayki Reyes and Lizbeth L{\'o}pez-Carrillo and Rogelio Recio and Javier Mor{\'a}n-Mart{\'i}nez and Mariano Enrique Cebrian and Betzabet Quintanilla-Vega},
  journal={Toxicology and applied pharmacology},
  year={2004},
  volume={196 1},
  pages={108-13}
}
Our objective was to evaluate alterations in sperm chromatin structure in men occupationally exposed to a mixture of organophosphorus pesticides (OP) because these alterations have been proposed to compromise male fertility and offspring development. Chromatin susceptibility to in situ acid-induced denaturation structure was assessed by the sperm chromatin structure assay (SCSA). Urinary levels of alkylphosphates (DAP) were used to assess exposure. Diethylthiophosphate (DETP) was the most… CONTINUE READING

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