Neuropathology of organophosphate-induced delayed neuropathy (OPIDN) in young chicks
- Biology, MedicineArchives of Toxicology
It is demonstrated that after neuropathic DFP exposure, 2-week-old chicks develop pathological lesions in the spinal cord without neurological deficits, and the claim of apparent age resistance of chicks to OPIDN needs to be re-evaluated.
Peripheral Nervous System Effects and Delayed Neuropathy
- Biology, Medicine
Organophosphate-Induced Delayed Polyneuropathy
- BiologyToxicological reviews
This article mainly discusses OP pesticide poisoning, particularly when caused by chlorpyrifos, dichlorvos, isofenphos, methamidophos, mipafox, trichlorfon,trichlornat, phosphamidon/mevinphos and by certain carbamates.
Promotion of organophosphate induced delayed polyneuropathy by certain esterase inhibitors.
Peripheral nerve esterases and the promotion of organophosphate-induced neuropathy in hens.
- BiologyChemico-biological interactions
Soluble phenyl valerate esterases of hen sciatic nerve and the potentiation of organophosphate induced delayed polyneuropathy.
- Biology, ChemistryChemico-biological interactions
Potentiation of organophosphorus-induced delayed neurotoxicity following phenyl saligenin phosphate exposures in 2-, 5-, and 8-week-old chickens.
- Biology, PsychologyFundamental and applied toxicology : official journal of the Society of Toxicology
It is concluded that posttreatment with neuropathic or nonneuropathic NTE inhibitors, following virtually complete NTE inhibition by either single or repeated doses of a neuropathic agent in sensitive age groups, can modify both the clinical and morphological indices of delayed neurotoxicity.
Effects of various post-treatment by phenylmethylsulfonyl fluoride on delayed neurotoxicity induced by leptophos.
- BiologyThe Journal of toxicological sciences
It is indicated that post-treatment with PMSF promotes leptophos-induced OPIDN and reduces the period to OPIDn onset and variations in both the dose and the time intervals of PMSF post- Treatment suggest that PMSF should not be used for either the treatment or the prevention ofOPIDN.
SHOWING 1-10 OF 11 REFERENCES
Age sensitivity to organophosphate-induced delayed polyneuropathy. Biochemical and toxicological studies in developing chicks.
- BiologyBiochemical pharmacology
Promotion of organophosphate-induced delayed polyneuropathy by phenylmethanesulfonyl fluoride.
- Biology, ChemistryToxicology and applied pharmacology
The pathogenesis of organophosphate polyneuropathy.
- BiologyCritical reviews in toxicology
This review discusses the facts regarding organophosphate-induced delayed polyneuropathy (OPIDP) as they are related to its pathogenesis rather than being a comprehensive review of all available…
Potentiation of organophosphorus-induced delayed neurotoxicity by phenylmethylsulfonyl fluoride.
- Biology, ChemistryJournal of toxicology and environmental health
The data indicate that PMSF only protects against OPIDN if given prior to exposure to the neurotoxicant; treatment with PMSF after OP exposure critically exacerbates the delayed neurotoxicity from exposure to organophosphorus compounds.
Central-peripheral delayed neuropathy caused by diisopropyl phosphorofluoridate (DFP): segregation of peripheral nerve and spinal cord effects using biochemical, clinical, and morphological criteria.
- Medicine, BiologyToxicology and applied pharmacology
Protection by some Carbamates against the Delayed Neurotoxic Effects of Di-isopropyl Phosphorofluoridate
The effect produced by di-isopropyl phosphorofluoridate (DFP) is studied because it is a potent neurotoxic compound and does not need to be metabolized to produce the active agent.
Neurotoxic esterase in peripheral nerve: assay, inhibition, and rate of resynthesis.
- Biology, MedicineToxicology and applied pharmacology
Acute Tricresylphosphate Intoxication in Childhood
- Medicine, PsychologyHuman toxicology
A case of severe intoxication in a 4½-year-old child following ingestion of a lubricant containing TCP is reported, typical of previously reported acute ingestions in adults.
Jamaica ginger paralysis. Forty-seven-year follow-up.
- Medicine, PsychologyArchives of neurology
In 1930, thousands of Americans were poisoned by an illicit extract of Jamaica ginger ("jake") used to circumvent the Prohibition laws. A neurotoxic organophosphate compound, triorthocresyl phosphate…
Purification of Neuropathy Target Esterase from Avian Brain After Prelabelling with [3H]Diisopropyl Phosphorofluoridate
- Biology, ChemistryJournal of neurochemistry
Neuropathy target esterase from hen brains was radiolabelled at the active site with [3H]diisopropyl phosphorofluoridate and the 150‐kDa subunit polypeptide appears as a single band on analytical SDS‐PAGE.