Organophosphate pesticides increase the expression of alpha glutathione S-transferase in HepG2 cells.

Abstract

Chlorpyrifos and methyl parathion are among the most widely used insecticides in the world. Human populations are constantly exposed to low doses of both due to their extensive use and presence in food and drinking water. Glutathione S-transferase (GST) catalyzes the conjugation of glutathione on electrophilic substrates and is an important line of defense… (More)
DOI: 10.1016/j.tiv.2011.08.010

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